Occurrence of T-strains and other mycoplasmata in non-gonococcal urethritis.
نویسندگان
چکیده
Dienes and Edsall (1937) isolated a strain ofmycoplasma from a patient with a Bartholin's gland abscess, and this became a prelude to numerous studies in which attempts were made to demonstrate the aetiological significance of mycoplasmata in inflammatory conditions of the lower genito-urinary tract, including particularly non-gonococcal urethritis (NGU). However, the results obtained were widely different, with isolation rates ranging from 7 per cent. (Salaman, King, Bell, Wilkinson, Gallagher, Kirk, Howorth, and Keppich, 1946) to 53 per cent. (Shepard, 1954). Freundt (1956) found mycoplasma species in the urethra in 53 6 per cent. of 28 healthy men, as compared with only 30 per cent. and 50 per cent. in patients with NGU and sub-clinical NGU. In addition, when KlienebergerNobel (1959) found a higher incidence of mycoplasmata in the male urethra in patients with gonorrhoea (48 per cent.) than in those with NGU (26 per cent.), it became difficult to continue to accept the possible significance of classic mycoplasma strains as an aetiological factor in NGU, even though the importance of differences in the mode of selection of patients and methods of investigation could not be overlooked. However, at the present time, most investigators seem to be inclined to interpret the classic mycoplasma strains ("large-colony strains") as saprophytes or commensals in the male urethra. It should be noted that the isolated strains in nearly all cases in which typing was performed were Mycoplasma homonis. Shepard (1954) observed, among typical mycoplasma colonies, some minute colonies, which he called T-strain mycoplasma (T for tiny). However, Klieneberger-Nobel (1959) queried the classification
منابع مشابه
Controlled study of the prevalence of T strain mycoplasmata in males with non-gonococcal urethritis.
Shepard (1956) and Shepard, Alexander, Lunceford, and Campbell (1964) reported the isolation from men with non-gonococcal urethritis of a species of mycoplasma which formed very small colonies on culture. The organisms were isolated from 86 per cent. of 79 men in the first study and from 51 per cent. of 64 men in the second. This organism was subsequently called T strain mycoplasma. Ford, Rasmu...
متن کاملErythromycin in the treatment of non-gonococcal urethritis.
Erythromycin was first used by the author in the treatment of non-gonococcal urethritis in 1954. Using relatively small doses of 100 mg. four times a day for 6 days in 25 male cases the re-treatment rate within 3 months was 33 3 per cent. of those followed (Willcox, 1954). A further series was then undertaken using 300 mg. four times a day for 5 days (Willcox, 1955a, 1955b), which was finally e...
متن کاملSingle dose piperacillin in treating uncomplicated gonococcal urethritis in men.
A single intramuscular dose of piperacillin 2 g, with probenecid 1 g orally, was used to treat 82 men with uncomplicated gonococcal urethritis due to penicillinase producing strains of Neisseria gonorrhoeae (PPNG) or non-PPNG. All 49 patients infected with non-PPNG strains were cured, as opposed to only 25 (76%) of 33 patients infected with PPNG strains, giving an overall success rate of 90%. N...
متن کاملT-strain pleuropneumonia-like organisms as one cause of non-gonococcal urethritis.
A recent study and review of the literature (Ford, 1960) provided no support for the view that the usual strains of genital pleuropneumonia-like organisms (PPLU) were a cause of non-gonococcal urethritis (NGU). It was noted, however, that Shepard (1956, 1957, 1960) had isolated morphologically distinct T-strain PPLO from the genital tract of patients with NGU, and that he believed these T-strai...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- The British journal of venereal diseases
دوره 44 4 شماره
صفحات -
تاریخ انتشار 1968